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Updated: May 25, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
Fatty emaciation: a case report of suspected fat overload syndrome in oral refeeding
Arielle D Macher1, Daniel Palazuelos, Saverio M Maviglia
1Department of Medicine, Hospitalist Service, Brigham and Women's Hospital, Boston, Massachusetts 02155, USA. amacher@partners.org
Abstract:
Refeeding syndrome has been observed in patients receiving nutrition after a prolonged period of malnourishment and is characterized by multiple metabolic derangements. Besides hypophosphatemia and hypoglycemia, lipemia has been described in association with parenteral nutrition administration to the malnourished. The authors describe one anorexic patient who developed lipemia during oral refeeding, followed by a precipitous drop in hematocrit suggestive of fat overload syndrome.
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