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A Comprehensive Procedure to Evaluate the In Vivo Performance of Cancer Nanomedicines
07:59

A Comprehensive Procedure to Evaluate the In Vivo Performance of Cancer Nanomedicines

Published on: March 4, 2017

Nanoparticle delivery systems for cancer therapy: advances in clinical and preclinical research

Susana Patricia Egusquiaguirre1, Manuela Igartua, Rosa María Hernández

  • 1NanoBioCel Group, Laboratory of Pharmaceutics, University of the Basque Country, School of Pharmacy, Vitoria, Álava, Spain.

Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
|February 4, 2012
PubMed

Insights

Nanotechnology offers a promising alternative to conventional cancer therapy by using nanoparticle drug delivery systems to target cancer cells. Further research is needed to overcome limitations and enhance treatment efficacy.

Area of Science:

  • Oncology
  • Nanotechnology
  • Drug Delivery

Background:

  • Conventional anticancer drugs have significant limitations in cancer therapy.
  • Nanotechnology presents a promising alternative for effective cancer treatment.
  • Nanoparticle drug delivery systems exploit tumor characteristics for targeted payload delivery.

Purpose of the Study:

  • To review the potential of nanoparticle delivery systems in cancer treatment.
  • To highlight current advances in nanotechnology for cancer therapy.

Main Methods:

  • Exploration of passive, active, and triggered targeting strategies.
  • Development of various nanoparticle types including liposomes, polymeric nanoparticles, and micelles.
  • Inclusion of polymer- or lipid-drug conjugates with cytotoxic therapeutics.

Main Results:

  • Nanoparticles can be engineered to improve drug properties and therapeutic index.
  • Several nanoparticle-based systems are in clinical and preclinical research.
  • Nanoparticle drug delivery systems show potential for selective cancer cell targeting.

Conclusions:

  • Nanoparticle drug delivery systems offer a promising approach to overcome limitations of traditional anticancer therapy.
  • Continued research and development are crucial for advancing nanotechnology in cancer treatment.
  • Nanotechnology holds significant potential for improving cancer treatment outcomes.

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