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Updated: May 25, 2026

Pseudofracture: An Acute Peripheral Tissue Trauma Model
Published on: April 18, 2011
Apophysomyces trapeziformis infection associated with a tornado-related injury
Gina Weddle1, Kimberly Gandy, Denise Bratcher
1Children's Mercy Hospitals and Clinics, University of Missouri, Kansas City, MO, USA. gweddle@cmh.edu
Abstract:
This report defines the role of Apophysomyces as an aggressive fungal pathogen seen after a tornado injury. Clinical and laboratory manifestations of infections after environmentally contaminated wounds incurred during a tornado are outlined, emphasizing mechanism of injury, comorbidities, and diagnostic and treatment challenges. Therapy with systemic antifungal therapy and aggressive serial tissue debridement was successful in achieving cure.
Insights
Apophysomyces fungi can cause aggressive infections following tornado injuries. Prompt treatment involving antifungal therapy and surgical debridement is crucial for successful recovery from these environmental fungal infections.
Area of Science:
- Mycology
- Infectious Diseases
- Trauma Surgery
Background:
- Tornadoes create unique injury patterns with high risk of environmental contamination.
- Fungal infections, particularly from rare molds, pose a significant threat in post-disaster scenarios.
- Understanding Apophysomyces's pathogenic role is critical for managing contaminated wounds.
Observation:
- Patients sustaining tornado injuries are at risk for aggressive fungal infections.
- Apophysomyces species are identified as a significant fungal pathogen in these cases.
- Clinical presentation includes manifestations of deep tissue infection from contaminated wounds.
Findings:
- Infections caused by Apophysomyces present diagnostic and treatment challenges.
- Systemic antifungal therapy is a key component of treatment.
- Aggressive serial tissue debridement is essential for achieving a cure.
Implications:
- Early recognition and management of Apophysomyces infections are vital for patient outcomes.
- This highlights the need for heightened surveillance of fungal infections after natural disasters.
- Effective treatment strategies combine antifungal medications with surgical intervention.
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