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The mechanism of acquired immunity in experimental giardiasis
S A Romia1, A A Abou-Zakham, M M Hegazi
1Department of Parasitology, Faculty of Medicine, Mansoura University, Egypt.
Journal of the Egyptian Society of Parasitology
|December 1, 1990
Abstract:
Giardia-spontaneously cured mice were rendered resistant to challenge infection. This was documented by the decreased cyst excretion rate comparable to the control ones. Endoxan and irradiation treatment caused a breakdown in both humoral and cellular immunity. Immune-depressed mice were more susceptible to Giardia infection, thus proving the active role of antibodies and cell-mediated immune response in giardiasis.