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Related Concept Videos

Translocation of Proteins into the Mitochondria01:19

Translocation of Proteins into the Mitochondria

Mitochondrial precursors are translocated to the internal subcompartments via independent mechanisms involving distinct protein machineries called translocases.
Sorting of outer membrane proteins:
Mitochondrial outer membrane proteins are of two types: the transmembrane, beta-barrel porins, and the membrane-anchored, alpha-helical proteins. Beta-barrel porin precursors are translocated by the TOM complex and inserted into the outer mitochondrial membrane by the SAM complex. In contrast,...
Mitochondria01:37

Mitochondria

Mitochondria are eukaryotic cellular organelles that are known to produce energy through a process called oxidative phosphorylation. Besides their primary function, mitochondria are involved in various cellular processes, including cell growth, differentiation, signaling, metabolism, and senescence. Age-related changes cause a decline in mitochondrial quality and integrity due to increased mitochondrial mutations and oxidative damage. Thus, aging can severely impact mitochondrial functions,...
Mitochondria01:37

Mitochondria

Mitochondria are eukaryotic cellular organelles that are known to produce energy through a process called oxidative phosphorylation. Besides their primary function, mitochondria are involved in various cellular processes, including cell growth, differentiation, signaling, metabolism, and senescence. Age-related changes cause a decline in mitochondrial quality and integrity due to increased mitochondrial mutations and oxidative damage. Thus, aging can severely impact mitochondrial functions,...
Overview of Metabolism01:40

Overview of Metabolism

Living cells constantly carry out various chemical reactions which are necessary for their proper functioning. These reactions are interlinked to one another via multiple pathways. The collection of these chemical reactions is known as metabolism.
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
Protein Transport to the Inner Chloroplast Membrane01:18

Protein Transport to the Inner Chloroplast Membrane

Proteins targeted to the inner chloroplast membrane, or plastid proteins, are transported by two general pathways: the stop-transfer and the re-insertion or post-import pathways. Most plastid proteins carry N-terminal transit sequences and internal import sequences targeting it to the specific chloroplast subcompartment. Proteins targeted by the stop-transfer pathway have internal hydrophobic sequences that inhibit their translocation into the stroma. As a result, these precursors are arrested...
Porin Insertion in the Outer Mitochondrial Membrane01:12

Porin Insertion in the Outer Mitochondrial Membrane

Porins are beta-barrel proteins translocated to the mitochondrial outer membrane through the TOM complex into the intermembrane space. Porin precursors bind TIM chaperones within the intermembrane space and are guided to the Sorting and Assembly Machinery complex or SAM complex on the outer mitochondrial membrane.
Three models describe the assembly of porins by the SAM complex and their insertion into the outer membrane. Model 1 suggests that porins are assembled outside the SAM channel as the...

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Related Experiment Video

Updated: May 25, 2026

Isolation and Respiratory Measurements of Mitochondria from Arabidopsis thaliana
09:54

Isolation and Respiratory Measurements of Mitochondria from Arabidopsis thaliana

Published on: January 5, 2018

Mitochondrial biogenesis and function in Arabidopsis.

A Harvey Millar, Ian D Small, David A Day

    The Arabidopsis Book
    |February 4, 2012
    PubMed
    Summary

    Mitochondria are vital for plant energy. Arabidopsis research reveals their complex roles in plant growth, metabolism, and signaling, highlighting the need for deeper understanding of these cellular powerhouses.

    Area of Science:

    • Plant Biology
    • Cellular Biology
    • Mitochondrial Research

    Background:

    • Mitochondria are essential for ATP synthesis, powering cellular functions.
    • Understanding plant mitochondrial complexity is crucial for comprehending growth and development.
    • Arabidopsis thaliana serves as a model organism for studying plant mitochondrial genetics and function.

    Purpose of the Study:

    • To review current evidence on mitochondrial components in plants.
    • To explore the roles of mitochondria in plant biogenesis, metabolism, and nuclear signaling.
    • To highlight the significance of mitochondrial research in plant science.

    Main Methods:

    • Utilizing Arabidopsis as a model system for genetic and molecular studies.
    • Analyzing gene expression data to understand mitochondrial component roles.

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    Published on: May 16, 2025

    Discrimintion and Mapping of the Primary and Processed Transcripts in Maize Mitochondrion Using a Circular RT-PCR-based Strategy
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    Discrimintion and Mapping of the Primary and Processed Transcripts in Maize Mitochondrion Using a Circular RT-PCR-based Strategy

    Published on: July 29, 2019

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    Last Updated: May 25, 2026

    Isolation and Respiratory Measurements of Mitochondria from Arabidopsis thaliana
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    Published on: January 5, 2018

    Preparation of Intact Tissue for Microscopic Analysis of the Endosperm Cell Layer in Developing and Mature Arabidopsis Seeds
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    Published on: May 16, 2025

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    Published on: July 29, 2019

  • Employing forward and reverse genetics to investigate mitochondrial function and impact.
  • Main Results:

    • Arabidopsis research has identified key mitochondrial components and their functions.
    • Genetic studies in Arabidopsis have linked mitochondrial dysfunction to significant impacts on plant metabolism and development.
    • Evidence points to mitochondrial involvement in signaling pathways to the nucleus.

    Conclusions:

    • Mitochondria play a multifaceted role in plant growth and development beyond ATP synthesis.
    • Further research into mitochondrial biogenesis, metabolism, and signaling is essential for advancing plant science.
    • Arabidopsis provides a powerful platform for dissecting mitochondrial functions in plants.