Haematological changes observed in Swiss albino mice infected with normal and gamma-irradiated E. granulosus larvae

Five groups of Swiss albino mice (Mus Musculus albinus) were intraperitoneally inoculated with 2,000 aseptic normal (control group) and gamma irradiated E. granulosus, larvae at different dose levels of 40 Kr, 60 Kr, 80 Kr and 100 Kr, respectively. Haematological studies showed a marked leucocytosis, a progressive increase in the average percentage of eosinophils as well as a great successive decrease in haemoglobin concentration through out the time of infection in control group as compared to the treated ones. Meanwhile the leucocytic count and the Haemoglobin concentration in treated mice was dose dependent as well as time dependent whereas the eosinophil percentage was only dose dependent rather than time dependent.