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Related Concept Videos

Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not necessarily...
Drug Dependence01:17

Drug Dependence

Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Stimulants01:29

Stimulants

Stimulants are substances that enhance neural activity and elevate dopamine levels in the brain, leading to their highly addictive nature. These drugs include cocaine, amphetamines, MDMA, caffeine, and nicotine, each with distinct mechanisms of action and varied health implications.
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
CNS Depressants: Alcohol and Nicotine01:27

CNS Depressants: Alcohol and Nicotine

Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
Depressants01:28

Depressants

Depressant drugs, including alcohol and sedative-hypnotics, diminish central nervous system activity by enhancing the action of gamma-aminobutyric acid (GABA), a neurotransmitter that reduces brain activity and promotes relaxation. These substances can have various therapeutic uses but also pose significant risks, especially when misused or combined.
Alcohol is a common depressant that can induce a sense of relaxation and reduced inhibition at low doses. Contrary to its occasional...

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Updated: May 25, 2026

Comprehensive Analysis of Transcription Dynamics from Brain Samples Following Behavioral Experience
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Published on: August 26, 2014

[Addiction].

J Besson1, J Grivel, A Tomei

  • 1Service de psychiatrie communautaire, CHUV, Lausanne. Jacques.Besson@chuv.ch

Revue Medicale Suisse
|February 7, 2012
PubMed
Summary
This summary is machine-generated.

In 2011, addiction medicine advanced with neuroscience insights and integrated care models. New approaches include cocaine vaccination ethics and mindfulness for addiction treatment.

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Area of Science:

  • Neuroscience
  • Clinical Medicine

Context:

  • Advances in addiction medicine in 2011.
  • Emerging trends in addiction treatment and research.

Purpose:

  • To review key developments in addiction medicine for 2011.
  • To highlight new knowledge from neurosciences and clinical practice.

Summary:

  • New insights from neurosciences are shaping addiction medicine.
  • The role of hospital addiction units within integrated care networks is emphasized.
  • Ethical considerations of cocaine vaccination are explored.
  • Mindfulness techniques are presented as a valuable tool for addiction treatment.

Impact:

  • Provides a comprehensive overview of 2011's significant contributions to addiction medicine.
  • Informs clinicians and researchers about the latest advancements and ethical debates.
  • Suggests future directions for integrated care and therapeutic interventions.