Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Mechanism of Filopodia Formation

Mechanism of Filopodia Formation

Filopodia are thin, actin-rich cellular protrusions that play an important role in many fundamental cellular functions. They vary in their occurrence, length, and positioning in different cell types, suggesting their diverse roles.
Their main function is to guide migrating cells during normal tissue morphogenesis or cancer metastasis by recognizing and making initial contacts with the extracellular matrix. However, they can also act as stationary cell anchors or help to establish communication...

Adaptability of Cytoskeletal Filaments

Adaptability of Cytoskeletal Filaments

The cytoskeleton is a complex dynamic structure performing varied functions based on cellular requirements. The adaptability of the individual filaments in the cytoskeleton determines their ability to perform various functions within the cell. It can undergo rapid reorganization during processes like cell division or remain stable for several hours as in the interphase. The adaptability of these filaments depends on stringent regulatory mechanisms. The microfilament and microtubules of the...

Disassembly of Intermediate Filaments

Disassembly of Intermediate Filaments

Intermediate filaments (IFs) do not undergo spontaneous disassembly. Enzymes, kinases, and phosphatases add and remove phosphates from specific sites to regulate their disassembly. The IF concentration in the cytoplasm also regulates the disassembly. If the concentration crosses a threshold, it activates the protein kinases in the vicinity, allowing the phosphorylation of IFs.
Keratin proteins, found at the cell periphery near cell junctions, undergo a cycle of assembly and disassembly. In Type...

Generation of Straight or Branched Actin Filaments

Generation of Straight or Branched Actin Filaments

The straight or branched structure formation of actin filaments is controlled by nucleating proteins such as the formins and Arp2/3 complex. Formin-mediated assembly results in straight filaments, whereas Arp2/3 protein complex-mediated assembly results in branched actin filaments.
Arp2/3 Complex
Arp2/3 complex is a seven-subunit complex consisting of two proteins similar to actin- Arp2 and Arp3, and five other subunits that help keep Arp2 and Arp3 inactive. When required, the complex is...

Actin Filament Depolymerization

Actin Filament Depolymerization

Actin filaments (F-actin) are composed of actin subunits. The dissociation of actin monomers can occur from either end of F-actin. The rate of dissociation is faster from the minus-end or the pointed end, where the actin subunits exist with a bound ADP, together known as ADP-actin. The depolymerization of F-actin is aided by proteins, including the actin-depolymerizing factor (ADF) and cofilin family of proteins, gelsolin, and glia maturation factor (GMF).
In F-actin, the ADF/cofilin proteins...

Actin Polymerization and Cell Motility

Actin Polymerization and Cell Motility

Actin is a family of globular proteins that are highly abundant in eukaryotic cells. It makes up approximately 1-5% of total cell protein concentration. Actin monomers polymerize to form a complex network of polarized filaments, the actin cytoskeleton, that plays a crucial role in many cellular processes, including cell motility, division, endocytosis, and metastasis of cancer cells.
Actin cytoskeleton dynamics can produce pushing, pulling, and resistance forces that help the cell to migrate.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Morphology of the lips, cheeks, and the hard palate of the Egyptian water buffalo (<i>Bubalus bubalis</i>): a focus on histological, histochemical, and ultrastructural aspects.

Iranian journal of veterinary research·2022

Same author

Ultrastructural features on the oral cavity floor (tongue, sublingual caruncle) of the Egyptian water buffalo (Bubalus bubalis): gross, histology and scanning electron microscope.

Folia morphologica·2021

Same author

Leukemic infiltration in the settings of acute respiratory failure.

Oxford medical case reports·2019

Same author

A three-layer model for buckling of a human aortic segment under specific flow-pressure conditions.

International journal for numerical methods in biomedical engineering·2014

Same author

Stability and relapse after orthodontic treatment of deep bite cases-a long-term follow-up study.

European journal of orthodontics·2012

Same author

Experiments on vertical slender flexible cylinders clamped at both ends and subjected to axial flow.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences·2007

Search research articles

Related Experiment Video

Updated: May 25, 2026

Using Microfluidics and Fluorescence Microscopy to Study the Assembly Dynamics of Single Actin Filaments and Bundles

Using Microfluidics and Fluorescence Microscopy to Study the Assembly Dynamics of Single Actin Filaments and Bundles

Published on: May 5, 2022

Flapping dynamics of a flexible filament.

H Ait Abderrahmane¹, M P Paidoussis, M Fayed

¹Department of Mechanical Engineering, McGill University, Montreal, Quebec H3A2K6, Canada.

Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics

|February 7, 2012

Summary

This study explores filament flapping in soap-film flow, revealing a quasiperiodic onset that transitions to chaos. A novel "switching oscillation" bistability phenomenon was discovered, where the filament continuously alternates states without external triggers.

More Related Videos

Flapping Soft Fin Deformation Modeling using Planar Laser-Induced Fluorescence Imaging

Flapping Soft Fin Deformation Modeling using Planar Laser-Induced Fluorescence Imaging

Published on: April 28, 2022

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers

Published on: October 25, 2017

Related Experiment Videos

Last Updated: May 25, 2026

Using Microfluidics and Fluorescence Microscopy to Study the Assembly Dynamics of Single Actin Filaments and Bundles

Using Microfluidics and Fluorescence Microscopy to Study the Assembly Dynamics of Single Actin Filaments and Bundles

Published on: May 5, 2022

Flapping Soft Fin Deformation Modeling using Planar Laser-Induced Fluorescence Imaging

Flapping Soft Fin Deformation Modeling using Planar Laser-Induced Fluorescence Imaging

Published on: April 28, 2022

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers

Published on: October 25, 2017

Area of Science:

Fluid dynamics
Nonlinear dynamics
Complex systems

Background:

Filament dynamics in fluid flow are crucial for understanding phenomena from biological locomotion to engineering applications.
Previous studies on filament behavior in flows have observed various dynamic regimes, but the transition to chaos and novel bistability remain areas for exploration.

Purpose of the Study:

To investigate the flapping dynamics of a filament in a two-dimensional soap-film flow.
To characterize the transition to chaotic behavior and identify new dynamic phenomena.
To explore the influence of filament length and flow speed on these dynamics.

Main Methods:

Experimental setup involving a filament in a two-dimensional soap-film flow.
Systematic variation of filament lengths and flow speeds.
Observation and analysis of flapping regimes, including amplitude and frequency modulation.

Main Results:

The onset of flapping was identified as quasiperiodic, characterized by amplitude and frequency modulation.
At higher flow velocities, the system exhibits chaotic oscillations, transitioning via the quasiperiodic route to chaos.
A novel bistability phenomenon, termed "switching oscillation," was discovered, where the system continuously alternates between stretched-straight and oscillatory states without external perturbation.

Conclusions:

The study elucidates the complex dynamics of filament flapping in soap-film flow, including the route to chaos.
The newly discovered
switching oscillation
phenomenon offers new insights into bistability in fluid-structure interactions.
These findings contribute to the fundamental understanding of nonlinear dynamics in fluid flows.