Hemopressin forms self-assembled fibrillar nanostructures under physiologically relevant conditions

Martha G Bomar1, Steven J Samuelsson, Patrick Kibler

  • 1Center for Advanced Drug Research (CADRE), SRI International , 140 Research Drive, Harrisonburg, Virginia 22802, United States.

Biomacromolecules
|February 7, 2012
PubMed
Summary

Hemopressin, a hemoglobin-derived peptide, self-assembles into beta-like fibrils under physiological conditions. This structural insight is crucial for understanding its therapeutic potential and CB1 receptor inverse agonism.

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