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Related Experiment Video

Updated: May 25, 2026

Phenotypic Analysis of Rodent Malaria Parasite Asexual and Sexual Blood Stages and Mosquito Stages

Phenotypic Analysis of Rodent Malaria Parasite Asexual and Sexual Blood Stages and Mosquito Stages

Published on: May 30, 2019

Global malaria mortality between 1980 and 2010: a systematic analysis.

Christopher J L Murray¹, Lisa C Rosenfeld, Stephen S Lim

¹Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA 98121, USA.

Lancet (London, England)

|February 7, 2012

Summary

This summary is machine-generated.

Malaria deaths peaked in 2004 and decreased by 2010, but the overall burden, especially in adults, remains higher than previously thought. Increased donor support is crucial for malaria elimination efforts.

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Published on: January 15, 2020

Area of Science:

Global Health
Epidemiology
Infectious Disease Modeling

Background:

Renewed global and national efforts to combat malaria have set ambitious goals.
Accurate assessment of malaria mortality trends is essential for evaluating progress and focusing future interventions.

Purpose of the Study:

To provide an accurate assessment of malaria mortality levels and time trends from 1980 to 2010.
To inform progress evaluation and guide future malaria control strategies.

Main Methods:

Systematic collection and correction of malaria mortality data (1980-2010).
Development of ensemble predictive models incorporating Plasmodium falciparum prevalence, drug resistance, and vector control.
Utilized out-of-sample predictive validity for final model selection.

Main Results:

Global malaria deaths peaked in 2004 (1.8M) and declined to 1.2M by 2010.
African malaria deaths increased to 1.6M in 2004, then decreased ~30% to 1.1M by 2010.
Estimated higher mortality in adults (>5 years) than previously reported.

Conclusions:

Malaria mortality burden is greater than previously estimated, particularly in adults.
Significant reduction in African malaria mortality attributed to scaled-up control activities.
Sustained and increased donor support is vital for achieving malaria elimination and broader health goals.