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Updated: May 25, 2026
Isolation of Leukocytes from the Human Maternal-fetal Interface
Published on: May 21, 2015
[Haemophagocytic syndrome in pregnancy: a case report]
K Hannebicque-Montaigne1, A Le Roc'h, D Launay
1Service de gynécologie obstétrique, hôpital Jeanne-de-Flandre, centre hospitalier régional universitaire de Lille, université Lille 2, 59037 Lille, France. montaigne.k@wanadoo.fr
Abstract:
Haemophagocytic syndrome (HPS) results from an inappropriate stimulation of macrophages in bone marrow and lymphoid organs, leading to haemophagocytosis and hypercytokinemia. HPS may be primitive, essentially in pediatric population, or secondary to malignancy, infection or autoimmune disease. This disease is rare and prognosis is poor. A small number of cases during pregnancy have been described in literature. We report one HPS case in a pregnant patient at 21 week's gestation with systemic lupus erythematosus. We discuss diagnostic difficulties, obstetrical complications and therapeutic options.
