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Related Experiment Videos

Endolymphatic hydrops precipitated by haemodialysis.

D A Moffat1, V L Cumberworth, D M Baguley

  • 1Department of Otolaryngology, Addenbrooke's Hospital, Cambridge.

The Journal of Laryngology and Otology
|August 1, 1990
PubMed
Summary

Hemodialysis can trigger endolymphatic hydrops in Meniere's disease patients, potentially by altering plasma osmolality. This case highlights a new risk factor for vestibular disorders.

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HNO·2018

Area of Science:

  • Otolaryngology
  • Nephrology
  • Neurology

Background:

  • Meniere's disease is a disorder of the inner ear.
  • Endolymphatic hydrops is characterized by excess fluid in the inner ear.
  • Hemodialysis is a treatment for kidney failure.

Observation:

  • A patient with Meniere's disease developed endolymphatic hydrops in the ear contralateral to previous episodes after hemodialysis.
  • Symptoms of Meniere's disease, including vertigo, tinnitus, and hearing loss, were induced during dialysis.
  • Audiometric and electrophysiological tests confirmed changes consistent with endolymphatic hydrops post-dialysis.

Findings:

  • Sudden decrease in plasma osmolality during hemodialysis may act as a "reverse glycerol test."
  • This osmolality shift is implicated in the precipitation of endolymphatic hydrops.

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  • The findings suggest a direct link between hemodialysis and inner ear fluid balance.

    • Implications:

    • Hemodialysis may be a precipitating factor for endolymphatic hydrops in susceptible individuals.
    • Understanding this mechanism could lead to preventive strategies for Meniere's disease patients undergoing dialysis.
    • This case broadens the understanding of factors influencing vestibular disorders.