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Identification of Cyclin-dependent Kinase 1 Specific Phosphorylation Sites by an In Vitro Kinase Assay
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Cyclin D1 is a NF-κB corepressor.

María F Rubio1, Pablo N Larrosa Fernandez, Cecilia V Alvarado

  • 1Laboratorio de Biología Molecular y Apoptosis, Instituto de Investigaciones Médicas Alfredo Lanari (IDIM-CONICET), Universidad de Buenos Aires, Combatientes de Malvinas 3150, C1427ARO Buenos Aires, Argentina.

Biochimica Et Biophysica Acta
|February 7, 2012
PubMed
Summary

Cyclin D1 (CD1) inhibits NF-κB activity, but RAC3 can reverse this effect. The balance of CD1 and RAC3 expression influences tumor cell proliferation, impacting cancer progression.

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