Related Experiment Video
Updated: May 25, 2026

Assessment of Glutamine as a Fuel Source for Alveolar Macrophages Exposed to Chronic Ethanol Using an Extracellular Flux Bioanalyzer
Published on: November 15, 2024
Alcoholic ketoacidosis coincides with acute Marchiafava-Bignami disease
1Department of Medicine, Taoyuan Armed Forces General Hospital, Taoyuan, Taiwan.
Abstract:
Alcoholism is the major cause of electrolyte and acid-base imbalance and nutrition deficiency. Ketoacidosis is one of major advised effect on alcoholism. Marchiafava-Bignami disease, a rare alcohol-related disorder, characterized by altered mental status, seizure, and multifocal central nervous system signs, which results from progressive demyelination and necrosis of corpus callosum. Here, we presented a 53-year-old man presented as decreased conscious level and 4 extremity rigidity on admission. Alcoholic ketoacidosis coincided with acute Marchiafava-Bignami disease had been confirmed by biochemistry examination and cranial magnetic resonance imaging. Aggressive hydration with 5% dextrose in normal saline and intravenous vitamin B complex were administered. The patient's symptoms completely recovered after ketoacidosis has been corrected 2 days later.
Related Concept Videos
Diabetic Ketoacidosis l: Introduction
Diabetic Ketoacidosis ll: Pathophysiology
Complications of Diabetes Mellitus
Acute Pancreatitis II: Pathophysiology
Acute Pancreatitis II: Clinical Manifestations and Management
Chronic Pancreatitis II: Pathophysiology