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Related Experiment Video

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Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke

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Poststroke fatigue: does group education make a difference? A randomized pilot trial.

Annabel Clarke1, Suzanne L Barker-Collo, Valery L Feigin

  • 1Department of Psychology, University of Auckland, Auckland, New Zealand.

Topics in Stroke Rehabilitation
|February 7, 2012
PubMed
Summary
This summary is machine-generated.

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This pilot study suggests an educational fatigue management program may help stroke survivors reduce fatigue. Further research is warranted to confirm these promising findings for stroke recovery.

Area of Science:

  • Neurology
  • Rehabilitation Medicine
  • Clinical Psychology

Background:

  • Fatigue is a prevalent issue impacting stroke survivor outcomes.
  • Educational fatigue management has shown efficacy in other chronic conditions like cancer.
  • Limited evidence exists for fatigue management interventions specifically in stroke patients.

Purpose of the Study:

  • To evaluate the feasibility and preliminary efficacy of an educational fatigue management intervention for stroke survivors.
  • To assess the impact of the intervention on fatigue severity and related quality of life measures.
  • To provide evidence for a larger, definitive trial.

Main Methods:

  • A pilot randomized controlled trial involving 19 stroke survivors experiencing significant fatigue (Fatigue Severity Scale score >3.9).

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Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke
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Published on: June 6, 2025

  • Participants were assigned to either a Fatigue Management Group (FMG) or a General Stroke Education (GSE) control group.
  • Assessments included the Fatigue Severity Scale (FSS), SF-36 social functioning, and Hospital Anxiety Depression Scale (HADS) at baseline, post-intervention, and 3-month follow-up.
  • Main Results:

    • Both groups demonstrated significant reductions in FSS fatigue scores from baseline to post-intervention.
    • While not statistically significant (P>0.05), the FMG group showed a greater decrease in FSS scores compared to the GSE group.
    • Significant improvements were observed in SF-36 social functioning and HADS depression scores, with no significant inter-group differences (P>0.05).

    Conclusions:

    • The educational fatigue management intervention (FMG) appears feasible for stroke survivors.
    • The positive trends suggest the intervention warrants further investigation in a full-scale clinical trial.
    • This approach holds potential for improving fatigue and related outcomes in post-stroke populations.