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Nutritional stress proteins in Candida albicans
N Dabrowa1, M L Zeuthen, D H Howard
1Department of Microbiology and Immunology, UCLA School of Medicine 90024.
Journal of General Microbiology
|July 1, 1990
Abstract:
Starving cells of Candida albicans synthesize at least seven proteins that represent nutritional-stress proteins (NSP). Such NSPs are formed by both germination-competent and germination-deficient strains of C. albicans. Heat-shock proteins (HSP) are not formed by starving cells. Germination-competent cells synthesize specific sets of proteins when incubated in a starvation medium that contains the germ-tube-inducing substances N-acetyl-D-glucosamine or L-proline. Both sets of induced proteins were also synthesized by a germination-deficient strain of C. albicans.