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Published on: November 5, 2019
The skeletal consequences of meningococcal septicaemia
1Paediatric Orthopaedic Surgery, Bristol Royal Hospital for Children, Upper Maudlin Street, Bristol, Avon BS2 8BJ, UK. fergal. monsell@uhbristol.nhs.uk
Insights
Meningococcal disease can cause severe limb complications in children. Surgical interventions like fasciotomy, amputation, realignment, and lengthening are crucial for managing these skeletal consequences and improving limb function.
Area of Science:
- Pediatric critical care
- Orthopedic surgery
- Infectious disease management
Background:
- Meningococcal disease is a significant cause of child mortality in the UK.
- Improved resuscitation has increased survival rates for severely ill children.
- Long-term skeletal complications of meningococcal disease are increasingly recognized.
Purpose of the Study:
- To describe the immediate management of ischemic limbs in critically ill children.
- To consider indications for fasciotomy and amputation.
- To review surgical algorithms for long-term limb salvage and amputee management.
Main Methods:
- Review of immediate management strategies for ischemic limbs in pediatric patients.
- Evaluation of indications for surgical interventions such as fasciotomy and amputation.
- Analysis of contemporary surgical techniques for limb realignment, lengthening, and prosthetic fitting.
Main Results:
- Ischemic limb management requires prompt attention in hemodynamically unstable children.
- Limb malalignment and soft tissue injury contribute to long-term disability.
- Surgical interventions can enhance function in surviving limbs and manage challenges in amputees.
Conclusions:
- Effective surgical algorithms are evolving to address the skeletal consequences of meningococcal disease.
- Management requires a multidisciplinary approach, from acute care to long-term rehabilitation.
- Surgical strategies aim to optimize limb function and minimize disability in affected children.
Abstract:
Meningococcal disease remains a leading cause of childhood mortality in the UK. Advances in resuscitation have resulted in survival of severely affected individuals and the long-term skeletal consequences are being increasingly recognised. The immediate management of the ischaemic limb in the context of a critically ill and haemodynamically unstable child is described and the indications for fasciotomy and amputation are considered. Long-term disability occurs as a consequence of limb malalignment and is often accompanied by significant injury to the soft tissue envelope. The function of surviving limbs can be enhanced using contemporary surgical techniques that involve realignment and lengthening. Amputees present specific difficulties due to the effect of remaining longitudinal growth on the function of the residual limb, and require surgical treatment that often continues throughout childhood. This overview considers the surgical algorithms that have evolved to treat these patients.
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