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Pure-tone auditory thresholds are not chronically elevated in multiple sclerosis.

Richard L Doty¹, Isabelle Tourbier, Sherrie Davis

¹Smell and Taste Center, University of Pennsylvania School of Medicine, 5 Ravdin Pavilion, 3400 Spruce Street, Philadelphia, PA 19104-4823, USA. doty@mail.med.upenn.edu

Behavioral Neuroscience

|February 8, 2012

Summary

This summary is machine-generated.

Multiple sclerosis (MS) does not appear to cause chronic pure-tone hearing loss. Hearing thresholds in MS patients were not linked to brain lesion activity, suggesting hearing issues are typically episodic.

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Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss

Published on: January 25, 2016

Area of Science:

Neurology
Audiology
Neuroimmunology

Background:

Consensus on chronic effects of multiple sclerosis (MS) on pure-tone thresholds is lacking.
Previous studies were limited by small sample sizes and lack of control groups.
The association between MS-related brain lesions and hearing thresholds has not been evaluated.

Purpose of the Study:

To investigate the chronic influence of MS on pure-tone hearing thresholds.
To assess the relationship between MS-related central brain lesions and pure-tone thresholds.

Main Methods:

Pure-tone thresholds (0.5–8 kHz) were measured in 73 MS patients and 73 matched controls.
MRI-determined lesion activity was assessed in 26 central brain regions for 63 MS patients.
Statistical analyses were performed to identify correlations between hearing thresholds, MS, and lesion activity.

Main Results:

Hearing thresholds were significantly influenced by sex, age, and frequency, but not by MS.
No significant association was found between pure-tone thresholds and MS-related lesion activity in any brain region.
The study found no evidence of chronic pure-tone hearing loss associated with MS.

Conclusions:

Multiple sclerosis is not chronically associated with pure-tone hearing loss.
Pure-tone thresholds are unrelated to MS lesion activity in higher brain regions.
MS-related hearing deficits are likely episodic and linked to eighth nerve or brainstem lesions.