A fluorometric method for evaluation of pharmacological activity against intracellular Leishmania amastigotes
Pablo Bilbao-Ramos1, Sergio Sifontes-Rodríguez, María Auxiliadora Dea-Ayuela
1Departamento de Parasitología. Facultad de Farmacia, Universidad Complutense de Madrid, Plaza Ramón y Cajal s/n, 28040-Madrid, Spain.
Abstract:
In this work a simple and novel method to evaluate the efficacy of compounds on intracellular Leishmania amastigotes by using a fluorometric assay has been developed. The new method is sensitive, easy to perform and scalable for high throughput and therefore it could be validated for screening of new anti-leishmanial agents.
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