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Updated: May 25, 2026

Detrusor Underactivity Model in Rats by Conus Medullaris Transection
Published on: August 28, 2020
Pathophysiology of overactive bladder
Mai A Banakhar1, Tariq F Al-Shaiji, Magdy M Hassouna
1Toronto Western Hospital, Toronto, ON, M5T2S8, Canada. drmaibanakher@hotmail.com
Abstract:
Overactive bladder (OAB) is a common disorder that negatively affects the quality of life of our patients and carries a large socioeconomic burden. According to the International Continence Society, it is characterized as urinary urgency, with or without urge incontinence, usually, with frequency and nocturia in the absence of causative infection. The pathophysiology of this disease entity varies between neurogenic, myogenic, or idiopathic factors. This paper provides a review of the contemporary theories behind the pathophysiology of OAB.
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