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Related Concept Videos

Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics01:23

Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics

Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla.  Benzonatate operates peripherally within the respiratory tract by anesthetizing...
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Asthma-IV: Nursing Management01:30

Asthma-IV: Nursing Management

The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
Antiasthma Drugs: Leukotriene Modifiers01:19

Antiasthma Drugs: Leukotriene Modifiers

Leukotriene modifiers, or cysteinyl leukotriene receptor antagonists, are medications used to manage chronic asthma. These agents target specific inflammatory mediators produced during arachidonic acid metabolism, an essential process in generating inflammation in the body.
Leukotriene modifiers work through two distinct mechanisms:

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Related Experiment Video

Updated: May 25, 2026

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
05:31

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

Breastfeeding and lung function at school age: does maternal asthma modify the effect?

Cristian M Dogaru1, Marie-Pierre F Strippoli, Ben D Spycher

  • 1Institute of Social and Preventive Medicine, University of Bern, Switzerland.

American Journal of Respiratory and Critical Care Medicine
|February 8, 2012
PubMed
Summary

Breastfeeding for over four months, particularly in children of mothers with asthma, is linked to improved school-age lung function. This suggests a direct impact on lung development rather than protection against infections or allergies.

Related Experiment Videos

Last Updated: May 25, 2026

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
05:31

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

Area of Science:

  • Pediatric Pulmonology
  • Epidemiology
  • Maternal and Child Health

Background:

  • Conflicting evidence exists regarding breastfeeding's impact on lung function.
  • The potential modifying role of maternal asthma in this association is unclear.

Purpose of the Study:

  • To investigate the relationship between the duration of breastfeeding and lung function in school-aged children.
  • To determine if maternal asthma influences the association between breastfeeding and lung function.

Main Methods:

  • The Leicestershire Cohort Studies assessed breastfeeding duration, other exposures, and respiratory symptoms.
  • Lung function parameters including forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), and forced mid-expiratory flow (FEF50) were measured at age 12.
  • Multivariable linear regression analysis was used with 1,458 participants.

Main Results:

  • Longer breastfeeding duration (>4 months) was associated with higher forced mid-expiratory flow (FEF50) in all children.
  • In children of mothers with asthma, breastfeeding was also associated with increased forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV1).
  • These associations remained significant after adjusting for infant infections and childhood asthma/atopy.

Conclusions:

  • Breastfeeding for over four months is linked to enhanced lung function (FEF50) in school-aged children.
  • The positive effects on FVC and FEV1 were particularly evident in children whose mothers had asthma.
  • The findings suggest a direct effect of breastfeeding on lung growth, independent of early-life infections or atopy.