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Structural elucidation and bioactivity of biflavonoids from the stems of Wikstroemia taiwanensis
Li-Yin Chen1, Ih-Sheng Chen2, Chien-Fang Peng3
1Department of Pharmacy, Chia-Nan University of Pharmacy and Science, Tainan 71710, Taiwan.
International Journal of Molecular Sciences
|February 8, 2012
Abstract:
Three new biflavonoids, wikstaiwanones A-C (1-3), along with four known compounds (4-7) were isolated from the stems of Wikstroemia taiwanensis (Thymelaeaceae). Their structures were elucidated by spectroscopic analysis. Compounds 4 and 5 showed antitubercular activity against Mycobacterium tuberculosis with MIC values of 15 μg/mL, respectively.
