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Updated: May 25, 2026

Control of Eating Behavior Using a Novel Feedback System
Published on: May 8, 2018
CNS regulation of appetite
Joanne A Harrold1, Terry M Dovey, John E Blundell
1Human Ingestive Behaviour Laboratory, Department of Experimental Psychology, University of Liverpool, Eleanor Rathbone Building, Bedford Street South, Liverpool L69 7ZA, UK. harrold@liverpool.ac.uk
This review explores appetite regulation, integrating psychological factors with bodily signals and brain networks. Understanding both homeostatic and hedonic appetite controls is key to managing the obesity epidemic.
Area of Science:
- Biopsychology
- Neuroscience
- Physiology
Background:
- Appetite regulation involves complex interactions between psychological experiences and peripheral nutritional systems.
- Homeostatic control mechanisms are traditionally studied in obesity, but hedonic factors are increasingly recognized as critical in modern environments.
- The central nervous system (CNS) integrates signals from both psychological and physiological sources to regulate food intake.
Purpose of the Study:
- To review the biopsychological regulation of appetite.
- To explore the interplay between psychological states, peripheral nutritional signals, and CNS processing.
- To highlight the challenges and therapeutic targets in managing the obesity epidemic.
Main Methods:
- Literature review synthesizing research on appetite regulation.
- Analysis of biopsychological and neurobiological mechanisms governing food intake.
- Integration of homeostatic and hedonic perspectives on appetite control.
Main Results:
- Appetite regulation is a multifaceted process influenced by psychological factors and peripheral signals.
- Both homeostatic (energy balance) and hedonic (pleasure-seeking) drives significantly impact appetite.
- Understanding these complex mechanisms is crucial for addressing the obesity epidemic.
Conclusions:
- Effective appetite control is a vital therapeutic target for weight management.
- Combined strategies targeting both homeostatic and hedonic appetite mechanisms show the most promise.
- Further research into appetite regulation complexity is needed to combat obesity.
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