Related Experiment Video
Updated: May 25, 2026

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
Published on: August 22, 2012
Schistosomiasis in infants and pre-school-aged children in sub-Saharan Africa: implication for control
Uwem F Ekpo1, Akinola S Oluwole, Eniola M Abe
1Department of Biological Sciences, University of Agriculture, PMB 2240, Abeokuta 110001, Nigeria. ekpouf@unaab.edu.ng
Insights
Schistosomiasis infections are increasingly found in infants and young children in sub-Saharan Africa, challenging previous assumptions about disease epidemiology and control strategies. Current control programs often overlook this vulnerable age group, necessitating policy review for inclusive treatment and health education.
Area of Science:
- Neglected Tropical Diseases
- Parasitology
- Public Health
Background:
- Schistosomiasis control in sub-Saharan Africa has historically focused on school-aged children and adults.
- Emerging evidence highlights significant schistosomiasis prevalence in infants and pre-school-aged children (≤ 6 years) across multiple African nations.
Purpose of the Study:
- To review the epidemiology, transmission, and control of schistosomiasis in infants and pre-school-aged children in sub-Saharan Africa.
- To highlight the current exclusion of this age group from national control programs and advocate for policy changes.
Main Methods:
- Literature review of existing epidemiological data on schistosomiasis in young children.
- Analysis of prevalence rates and geographical distribution in affected countries.
- Assessment of current control program strategies and their limitations.
Main Results:
- Schistosomiasis infection begins in early childhood, contrary to prior assumptions.
- Prevalence rates in infants and pre-schoolers range from 14% to 86% in endemic areas.
- Factors influencing exposure in this age group remain largely undetermined.
Conclusions:
- Schistosomiasis morbidity can develop early in childhood, potentially leading to long-term clinical impact.
- Current control programs overlook the significant burden of schistosomiasis in infants and pre-school-aged children.
- Policy review is essential to include young children in treatment and health education initiatives for mothers.
Abstract:
Until recently, the epidemiology and control of schistosomiasis in sub-Saharan Africa have focused primarily on infections in school-aged children and to a lesser extent on adults. Now there is growing evidence and reports of infection in infants and pre-school-aged children (≤ 6 years old) in Ghana, Kenya, Mali, Niger, Nigeria and Uganda, with reported prevalence from 14% to 86%. In this review, we provide available information on the epidemiology, transmission and control of schistosomiasis in this age group, generally not considered or included in national schistosomiasis control programmes that are being implemented in several sub-Saharan African countries. Contrary to previous assumptions, we show that schistosomiasis infection starts from early childhood in many endemic communities and factors associated with exposure of infants and pre-school-aged children to infection are yet to be determined. The development of morbidity early in childhood may contribute to long-term clinical impact and severity of schistosomiasis before they receive treatment. Consistently, these issues are overlooked in most schistosomiasis control programmes. It is, therefore, necessary to review current policy of schistosomiasis control programmes in sub-Saharan Africa to consider the treatment of infant and pre-school-aged children and the health education to mothers.
Related Concept Videos
Fungal Phylum Microsporidia
Symbiosis
Anthelminthic Agents

