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Updated: May 25, 2026

Functional Characterization of Regulatory Macrophages That Inhibit Graft-reactive Immunity
Published on: June 7, 2017
Regulation of suppressive function of myeloid-derived suppressor cells by CD4+ T cells
Srinivas Nagaraj1, Dmitry I Gabrilovich
1Department of Internal Medicine, University of South Florida, Tampa, FL 33612, United States. snagaraj@health.usf.edu
Abstract:
Myeloid derived suppressor cells play a critical role in T cell suppression in cancer. Here, we discuss the mechanisms of how MDSC suppress CD4(+) or CD8(+) T cells in an antigen dependent or non-dependent manner.
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