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Acquired amegakaryocytic thrombocytopenia in a patient with occupational chemical exposure

Monaliben Patel1, Ankur Kalra, Rakesh Surapaneni

  • 1Divisions of 1Internal Medicine; and 2Hematology/Medical Oncology, Department of Medicine; and 3Department of Pathology, Cooper University Hospital, University of Medicine & Dentistry of New Jersey-Robert Wood Johnson Medical School, Camden, NJ.

American Journal of Therapeutics
|February 9, 2012
PubMed

Acquired amegakaryocytic thrombocytopenia (AAT) is a hematologic disorder that presents as thrombocytopenia with absent megakaryocytes in the bone marrow. Causes of AAT include toxins, drugs, viral infections, systemic lupus erythematosus, and cytokine deficiencies. Patients with AAT should be followed for possible progression to aplastic anemia or myelodysplastic syndrome. We present a case of a 61-year-old woman with AAT due to occupational chemical exposure.

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