Related Experiment Video

Updated: May 25, 2026

Production and Purification of Non Replicative Canine Adenovirus Type 2 Derived Vectors
14:55

Production and Purification of Non Replicative Canine Adenovirus Type 2 Derived Vectors

Published on: December 3, 2013

The evolutionary processes of canine coronaviruses

Annamaria Pratelli1

  • 1Department of Public Health and Animal Sciences, University of Bari, 70010 Valenzano, Bari, Italy.

Advances in Virology
|February 9, 2012
PubMed

Insights

Canine coronavirus (CCoV) has evolved significantly since its 1971 discovery, with new strains emerging due to its high mutation rate. Further research is needed to understand CCoV

Area of Science:

  • Veterinary Virology
  • Canine Infectious Diseases
  • Molecular Evolution

Background:

  • Canine coronavirus (CCoV) was first identified in 1971, but its role in canine enteric disease remains poorly understood.
  • Renewed interest in coronaviruses, spurred by the 2002 SARS emergence, has led to advancements in identifying CCoV strains.
  • RNA viruses like CCoV have high mutation frequencies, driving viral evolution and the emergence of new subtypes.

Purpose of the Study:

  • To investigate the evolutionary processes of canine coronaviruses (CCoVs).
  • To highlight recent advancements in diagnostic methods for CCoV infections.
  • To underscore the need for further research into CCoV biology and pathogenesis.

Main Methods:

  • Review of existing literature on CCoV evolution and epidemiology.
  • Analysis of biomolecular techniques developed over the last two decades.
  • Focus on identification of new CCoV strains, serotypes, and subtypes.

Main Results:

  • CCoV has evolved, with new strains and subtypes identified in infected dogs.
  • Biomolecular techniques have facilitated the detection of viral diversity.
  • Epidemiological studies indicate the widespread nature of CCoV infections.

Conclusions:

  • Canine coronavirus (CCoV) exhibits significant evolutionary dynamics.
  • Understanding CCoV evolution is crucial for effective disease management and control.
  • Continued investigation into CCoV pathogenesis and diagnostics is warranted.

More Related Videos

Generation of Recombinant Arenavirus for Vaccine Development in FDA-Approved Vero Cells10:03

Generation of Recombinant Arenavirus for Vaccine Development in FDA-Approved Vero Cells

Published on: August 1, 2013

Related Concept Videos

Viral Mutations00:36

Viral Mutations

A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material for adaptive...
Evolutionary Processes in Microbes01:26

Evolutionary Processes in Microbes

Microbial evolution occurs rapidly due to short generation times and a variety of genetic processes, including horizontal gene transfer, mutation, recombination, and genetic drift. These mechanisms collectively enable microbes to adapt swiftly to changing environments.Horizontal gene transfer (HGT) allows genes to move between different species and occurs through three main mechanisms: conjugation, transformation, and transduction. Conjugation involves direct cell-to-cell contact for DNA...
Viral Recombination00:57

Viral Recombination

Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
Evolution of New Traits in Microbes01:24

Evolution of New Traits in Microbes

Microorganisms evolve rapidly due to their large population sizes and short generation times, often exhibiting measurable changes within days under laboratory conditions. Natural selection acts on standing genetic variation, enabling the retention and amplification of beneficial traits that confer fitness advantages in changing environments.Adaptive Pigment Regulation in RhodobacterIn Rhodobacter, a genus of purple non-sulfur bacteria, light-harvesting pigments such as bacteriochlorophyll and...
Evolution of Microbial Genome01:08

Evolution of Microbial Genome

Microbial genome evolution is a highly dynamic process shaped by continual gene gain and loss across species and strains. This genomic flexibility allows microorganisms to adapt rapidly to environmental pressures and interactions with other organisms. Central to understanding this diversity is the distinction between the core and pan genomes.The core genome comprises the genes shared by all sampled strains of a species, representing essential functions needed for fundamental cellular processes.
Convergent Evolution01:54

Convergent Evolution

Evolution shapes the features of organisms over time, ensuring that they are suited for the environments in which they live. Sometimes, selection pressure leads to the rise of similar but unrelated adaptations in organisms with no recent common ancestors, a process known as convergent evolution.