Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Fungal Phylum Microsporidia

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...

Pulmonary Tuberculosis I

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...

Cytomegalovirus Disease

Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Radionuclide-stimulated dynamic therapy induces complementary immunogenic necroptosis and apoptosis cancer cell death pathways.

Communications biology·2026

Same author

Plazomicin in multidrug-resistant complicated urinary tract infections: a scoping review.

Therapeutic advances in infectious disease·2025

Same author

Deep learning model BiFPN-YOLOv8m for tree counting in mango orchards using satellite remote sensing data.

Scientific reports·2025

Same author

Management of infections caused by Extended-spectrum beta-lactamase-producing Enterobacterales in Indian patients.

Indian journal of medical microbiology·2025

Same author

A strategic approach to regulating new antimicrobials.

Journal of global health·2025

Same author

In-vitro activity of cefepime/enmetazobactam against extended spectrum beta-lactamases and/or ampC producing Enterobacterales and Pseudomonas aeruginosa collected across India.

Diagnostic microbiology and infectious disease·2025

Search research articles

Related Experiment Videos

Isolated cryptococcal osteomyelitis in immunocompetent patient.

Partha Karmakar¹, Ramanan Jeyarajah, V Ramasubramanian

¹Department of Medicine, Apollo Hospitals, Chennai 600006.

Journal of the Indian Medical Association

|February 10, 2012

Summary

This summary is machine-generated.

Isolated osteomyelitis caused by Cryptococcus neoformans is rare, especially in immunocompetent individuals. This report details a unique case in a 60-year-old woman, highlighting successful treatment with fluconazole.

Related Experiment Videos

Area of Science:

Mycology
Infectious Diseases
Orthopedics

Background:

Cryptococcosis is an opportunistic infection common in AIDS patients, typically presenting as meningitis.
Cryptococcal osteomyelitis is usually part of a disseminated infection.
Isolated cryptococcal osteomyelitis is exceptionally rare, particularly in immunocompetent individuals.

Observation:

A 60-year-old female presented with left clavicle pain and swelling.
Histopathological examination of a bone biopsy revealed organisms consistent with Cryptococcus.
The patient was immunocompetent.

Findings:

The case represents a rare instance of isolated osteomyelitis caused by Cryptococcus neoformans.
The patient's presentation and diagnostic findings confirmed the rare condition.
Microscopic analysis of bone tissue was crucial for diagnosis.

Implications:

This case expands the understanding of Cryptococcus neoformans' potential to cause isolated bone infections.
It underscores the importance of considering fungal infections in non-typical presentations, even in immunocompetent patients.
Successful treatment with fluconazole suggests its efficacy in managing rare forms of cryptococcal osteomyelitis.