Association between infant formula feeding and dental fluorosis and caries in Australian children

Loc G Do1, Steven M Levy, A John Spencer

  • 1Australian Research Centre for Population Oral Health, The University of Adelaide, Australia. loc.do@adelaide.edu.au

Insights

Infant formula use increased fluorosis risk in nonfluoridated areas but not fluoridated ones. Using non-tap water for formula in fluoridated areas was linked to higher caries experience in children.

Area of Science:

  • Pediatric Dentistry
  • Public Health
  • Fluoride Research

Background:

  • Dental fluorosis and caries are significant pediatric oral health concerns.
  • Infant feeding practices, particularly formula use, may influence these outcomes.
  • Understanding the role of water fluoridation and formula preparation is crucial for prevention.

Purpose of the Study:

  • To investigate the association between infant formula feeding patterns and dental fluorosis and caries.
  • To analyze these associations within the context of water fluoridation status in Australian children.

Main Methods:

  • A population-based study involving 588 Australian children aged 8-13 years.
  • Categorization of children based on infant formula use duration and water fluoridation status.
  • Assessment of dental fluorosis using the Thylstrup and Fejerskov (TF) Index and primary tooth caries experience from clinical records.

Main Results:

  • Children in fluoridated areas showed higher mild fluorosis but lower caries experience than those in nonfluoridated areas.
  • Prolonged infant formula use (6+ months) in nonfluoridated areas correlated with increased fluorosis prevalence.
  • In fluoridated areas, formula use with non-tap water was associated with higher caries experience.

Conclusions:

  • Infant formula use is linked to higher fluorosis prevalence in nonfluoridated environments.
  • Water source used for formula reconstitution in fluoridated areas impacts caries risk.
  • Public health strategies should consider water quality and infant feeding practices for optimal oral health.
Abstract

Related Concept Videos

Development of the Oral Microbiota01:28

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
Teeth01:15

Teeth

The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
Tooth Anatomy01:21

Tooth Anatomy

The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
Minerals01:26

Minerals

Minerals are essential nutrients that the human body needs in small amounts to work properly. They play a vital role in many bodily functions, such as building strong bones and transmitting nerve impulses. Some minerals are needed for hormone production or to maintain a normal heartbeat. Major minerals include calcium, phosphorus, potassium, sulfur, sodium, chlorine, and magnesium, while trace minerals include iron, manganese, copper, iodine, zinc, cobalt, fluoride, and selenium.
Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
The Oral Microbiota01:27

The Oral Microbiota

The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...