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Related Concept Videos

What are Lipids?01:38

What are Lipids?

Overview
What are Lipids?01:31

What are Lipids?

Lipids function as structural components of cellular membranes, in addition to acting as energy reservoirs and signaling molecules. They are thus crucial to all living organisms.  The three biologically important classes of lipids are triglycerides, phospholipids, and steroids.
Non-Polar and Hydrophobic Characteristics of Lipids
Lipids are a structurally and functionally diverse group of hydrocarbons—compounds consisting of carbon and hydrogen atoms. The carbon-carbon and carbon-hydrogen bonds...
What are Lipids?01:31

What are Lipids?

Lipids function as structural components of cellular membranes, in addition to acting as energy reservoirs and signaling molecules. They are thus crucial to all living organisms.  The three biologically important classes of lipids are triglycerides, phospholipids, and steroids.
Non-Polar and Hydrophobic Characteristics of Lipids
Lipids are a structurally and functionally diverse group of hydrocarbons—compounds consisting of carbon and hydrogen atoms. The carbon-carbon and carbon-hydrogen bonds...
What are Lipids?01:38

What are Lipids?

Overview
Overview of Lipid Metabolism01:24

Overview of Lipid Metabolism

Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
Lipid-derived Compounds in the Human Body01:31

Lipid-derived Compounds in the Human Body

Fats and lipids are crucial components in the human body. Some lipid-derived compounds, such as fat-soluble vitamins, eicosanoids, lipoproteins, and glycolipids, also play unique roles to support various  biological processes .
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin, delayed...

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Related Experiment Video

Updated: May 25, 2026

Shotgun Lipidomics of Rodent Tissues
11:46

Shotgun Lipidomics of Rodent Tissues

Published on: November 18, 2022

Lipidomics.

Anthony D Postle1

  • 1Clinical and Experimental Sciences, University of Southampton, Hampshire, UK. adp@soton.ac.uk

Current Opinion in Clinical Nutrition and Metabolic Care
|February 10, 2012
PubMed
Summary
This summary is machine-generated.

Lipidomics, the study of lipids, uses advanced mass spectrometry to identify disease biomarkers. Recent breakthroughs show its potential in understanding metabolic processes for conditions like diabetes and neurodegenerative diseases.

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Last Updated: May 25, 2026

Shotgun Lipidomics of Rodent Tissues
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Sample Preparation for Rapid Lipid Analysis in Drosophila Brain Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging
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Sample Preparation for Rapid Lipid Analysis in Drosophila Brain Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging

Published on: July 14, 2022

Area of Science:

  • Biochemistry
  • Analytical Chemistry
  • Systems Biology

Background:

  • Lipidomics analyzes intact lipid molecular species in biological systems.
  • The field has seen significant advancements in mass spectrometry (MS) instrumentation and applications.
  • This review focuses on recent progress and clinical applications of lipidomics.

Purpose of the Study:

  • Highlight recent advances in mass spectrometry for lipidomics.
  • Outline the application of these advances to clinical issues.
  • Demonstrate the potential of lipidomics in disease research.

Main Methods:

  • Review of recent advances in lipid detection and analysis using various MS techniques.
  • Exploration of specific applications: stable isotope labeling, MS imaging, data analysis, and bioinformatics.
  • Presentation of case studies applying lipidomics to selected disease states.

Main Results:

  • Identification of novel methodologies in lipid detection and analysis.
  • Demonstration of lipidomics applications in diabetes, neurodegenerative diseases, and respiratory diseases.
  • Highlighting the utility of lipidomics in generating disease biomarkers.

Conclusions:

  • Lipidomics is transitioning from methodology development to clinical application.
  • Recent advances confirm the potential of lipidomics for biomarker discovery.
  • Lipidomics offers insights into signaling and metabolic processes in various diseases.