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Automated Radiochemical Synthesis of [18F]3F4AP: A Novel PET Tracer for Imaging Demyelinating Diseases
Published on: May 29, 2017
A method to assess safety and resilience in radiopharmaceuticals production process
Cláudio H S Grecco1, Mario C R Vidal, Isaac J A L Santos
1Instituto de Engenharia Nuclear, Divisão de Instrumentação e Confiabilidade Humana, Rua Hélio de Almeida 75, Cidade Universitária - Ilha do Fundão, Rio de Janeiro, RJ, Brazil. agrecco@ien.gov.br
Abstract:
Radiopharmaceuticals are radiation-emitting substances used in medicine for radiotherapy and imaging diagnosis. A Research Institute, located in Rio de Janeiro, produces three radiopharmaceuticals: the sodium iodate is used in the diagnosis of thyroid dysfunctions, the meta-iodo-benzylguanidine is used in the diagnosis of cardiac diseases, and the fluordesoxyglucose is used in diagnosis in cardiology, oncology, neurology and neuropsychiatry. This paper presents a method to access safety and resilience in radiopharmaceuticals production processes. The method uses resilience indicators in order to proactively evaluate and manage the safety.
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