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Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery
Published on: November 5, 2019
[Invasive meningococcal disease--management and treatment]
Aleksander Garlicki1, Monika Bociqga-Jasik, Anna Kalinowska-Nowak
1Klinika Chorób Zakaźnych Collegium Medicum Uniwersytetu Jagiellońskiego.
Abstract:
Invasive meningococcal disease is life threatening disease and in fulminant cases mortality rate may be as high as 70%. Rapid introduction of treatment and monitoring on intensive care unit is crucial for prognosis. The understanding of patomechanism responsible for sepsis development allow to introduce supportive treatment including glicocorticoids and recombinant human activated protein C. Very important is suitable prophylaxis among risk groups with, additional considering vaccination in the case of infection caused by A, C, Y, W-135 serogroups.
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