Related Experiment Video
Updated: May 25, 2026

Cell Squeezing as a Robust, Microfluidic Intracellular Delivery Platform
Published on: November 7, 2013
Concept for a gas-cell-driven drug delivery system for therapeutic applications
1TU München, Heinz Nixdorf Lehrstuhl für Medizinische Elektronik, München, Germany. sven.becker@tum.de
Abstract:
This paper presents a concept for an implantable micro-pump based on hydrogen-generating gas cells. The gas-generating cell is separated from the drug reservoir by an expandable latex membrane. The system offers linear drug delivery with flowrates ranging from 8 nl/s to 2 microl/s and a total delivery volume of up to 160 ml. Drugs can be dispensed over a wide backpressure range. The device is scalable based on the size of the gas-producing cell and requires no external energy source. Possible fields of application include in vivo local drug delivery for chemotherapy, diabetes, and pain management.
Related Concept Videos
Modified-Release Drug Delivery Systems: Stimuli-Activated
Modified-Release Drug Delivery Systems: Site-Targeted
Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices
Modified-Release Drug Delivery Systems: Classification
Oral Drug Delivery Systems: Continuous-Release Systems
Modified-Release Drug Delivery Systems: Overview

