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A Permanent Window for Investigating Cancer Metastasis to the Lung
Published on: July 1, 2021
Vascular events in lung cancer
Nilgün Yilmaz Demirci1, Ülkü Yılmaz Turay, Aydın Yılmaz
1Pulmonary Department, Atatürk Chest Disease and Chest Surgery Training and Research Hospital, Ankara, Turkey. nilgundemirci@gmail.com
Asian Pacific Journal of Cancer Prevention : APJCP
|February 11, 2012
Summary
This study investigated thrombocytosis in lung cancer patients, finding no direct link to immediate vascular events. Further research is needed to explore prophylactic anticoagulant use in this population.
Area of Science:
- Oncology
- Hematology
- Pulmonology
Background:
- Thrombocytosis is a common finding in lung cancer patients.
- Vascular events are significant causes of morbidity and mortality in cancer patients.
- The prognostic significance of thrombocytosis in lung cancer requires further investigation.
Purpose of the Study:
- To evaluate the relationship between thrombocytosis and vascular events in lung cancer patients.
- To identify potential associations between thrombocytosis and paraneoplastic syndromes.
Main Methods:
- Retrospective analysis of 281 lung cancer patients diagnosed between March 2007 and August 2009.
- Statistical analysis included Shapiro-Wilk test, Pearson's chi-squared, Fisher's exact chi-squared, and Spearman's correlation tests.
- Data was analyzed using SPSS software (ver. 11.5 for Windows).
Main Results:
- The study included 281 patients (83.3% male, 16.7% female) with a median age of 60.6 years.
- Non-small cell lung cancer (NSCLC) was diagnosed in 85.8% of patients, and small-cell lung cancer (SCLC) in 14.2%.
- Seventeen vascular events were identified, including deep vein thrombosis (64.7%) and pulmonary thromboembolism (17.6%). Thrombocytosis was noted on subsequent visits, not during acute events.
Conclusions:
- Thrombocytosis is frequently observed in lung cancer patients.
- No direct association was found between thrombocytosis and immediate vascular events in this cohort.
- Prospective studies are recommended to assess the need for prophylactic anticoagulants and to evaluate the association between vascular events and survival.
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