Related Experiment Video

Updated: May 25, 2026

Pulse-Wave Velocity, Flow-Mediated Dilation, and Carotid Intima-Media Thickness to Assess Cardiovascular Risk in Population with Metabolic Syndrome
06:04

Pulse-Wave Velocity, Flow-Mediated Dilation, and Carotid Intima-Media Thickness to Assess Cardiovascular Risk in Population with Metabolic Syndrome

Published on: September 27, 2024

[Radial augmentation index is associated with cardiovascular risk and arterial stiffness]

Wen-kai Xiao1, Ping Ye, Lei-ming Luo

  • 1Second Department of Cardiology, PLA General Hospital, Beijing, China. xiaowk301@sina.com

Zhonghua Nei Ke Za Zhi
|February 11, 2012
PubMed

Insights

Radial augmentation index (AI) may indicate cardiovascular risk and arterial stiffness. This marker is more effective for differentiating risk in younger individuals compared to older ones.

Area of Science:

  • Cardiovascular physiology
  • Vascular biomechanics
  • Biomarker research

Context:

  • Arterial stiffness and cardiovascular risk are critical health concerns.
  • Augmentation index (AI) is a non-invasive measure of arterial function.
  • Existing research on AI's association with cardiovascular risk and arterial stiffness requires further investigation.

Purpose:

  • To determine if radial augmentation index (rAI) correlates with cardiovascular risk scores and arterial stiffness measures.
  • To explore the relationship between rAI, cardiovascular risk, and pulse wave velocity (PWV) in a large cohort.
  • To assess the influence of age on the association between rAI and cardiovascular parameters.

Summary:

  • A study of 4985 adults found radial augmentation index (rAI) was higher in women than men.
  • rAI showed significant correlations with cardiovascular risk scores and carotid-femoral PWV (CFPWV), particularly in men and younger individuals.
  • The association between rAI and arterial stiffness (CFPWV) was significant, but not with carotid-radial PWV (CRPWV).

Impact:

  • Radial AI may serve as a valuable, accessible marker for assessing cardiovascular risk and arterial stiffness.
  • The findings suggest rAI could be a practical tool for risk stratification, especially in younger populations.
  • This research contributes to understanding AI's role in cardiovascular health assessment and disease prevention.
Abstract

More Related Videos

Measuring Ascending Aortic Stiffness In Vivo in Mice Using Ultrasound10:08

Measuring Ascending Aortic Stiffness In Vivo in Mice Using Ultrasound

Published on: December 2, 2014

Related Concept Videos

Assessment of radial pulse01:11

Assessment of radial pulse

Assessment of Radial Pulse
The radial pulse, located at the wrist, is often the preferred site for assessing peripheral pulse because of its accessibility and dependability. The process of determining the radial pulse involves several steps:
Assessment of apical radial pulse01:25

Assessment of apical radial pulse

Apical-Radial (A-R) Pulse Assessment
The A-R pulse assessment involves simultaneous evaluation of the apical and radial pulses. When the apical and radial pulse rates vary, this assessment helps identify a pulse deficit.
Pre-Procedural Preparation
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...