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Use of a Rat Model to Study Ventral Abdominal Hernia Repair
Published on: October 2, 2017
[Inguinal hernia repair with acellular tissue matrix patch for pediatric patients aged 6 to 18 years]
Ying-mo Shen1, Jie Chen, Shuo Yang
1Department of Hernia and Abdominal Wall Surgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.
Insights
This study found that using an acellular tissue matrix patch for pediatric inguinal hernia repair (Lichtenstein herniorrhaphy) showed good results with limited complications. The patch demonstrated comparable safety and efficacy to traditional methods in young patients.
Area of Science:
- Pediatric Surgery
- Biomaterials in Surgery
- Hernia Repair
Context:
- Inguinal hernias are common in children.
- Traditional repair involves high ligation of the hernial sac.
- Acellular tissue matrix patches offer a potential alternative for hernia repair.
Purpose:
- To evaluate the safety and efficacy of acellular tissue matrix patch hernioplasty in pediatric patients (6-18 years).
- To compare outcomes of Lichtenstein herniorrhaphy with acellular tissue matrix patch versus traditional high ligation.
Summary:
- Sixty pediatric patients with inguinal hernias were randomized to receive either an acellular tissue matrix patch or traditional high ligation.
- Both groups showed similar postoperative stay, pain scores, and complication rates (hydrocele, infection, chronic pain).
- The acellular tissue matrix patch group had no recurrence, while the control group had a 6.7% recurrence rate, with no statistically significant difference.
Impact:
- Acellular tissue matrix patch hernioplasty is a safe and effective option for pediatric inguinal hernia repair.
- This technique shows promising results with a low complication profile in young patients.
- Further research may explore long-term outcomes and cost-effectiveness.
Objective:
To evaluate the safety and efficacy of hernioplasty using acellular tissue matrix patch to repair inguinal hernia of pediatric patients aged 6 to 18 years.
Methods:
Sixty eligible patients aged 6 to 18 years with primary unilateral inguinal hernia were randomly assigned to experimental or control group from June to December 2009. In the experimental group, acellular tissue matrix patch was used during Lichtenstein herniorrhaphy while traditional high ligation of hernial sac was used in the control group. Preoperative and postoperative parameters such as clinical informations of patients, postoperative complications and recurrence rate were recorded and analyzed.
Results:
There were no significant differences between the 2 groups in postoperative length of stay [(31 ± 8) h vs. (34 ± 11) h] and postoperative Visual Analogue Scale Pain Score (2.8 ± 0.9 vs. 2.6 ± 1.0) (P > 0.05), but the operation time in the experimental group were longer than that in the control group significantly [(39 ± 4) min vs. (36 ± 4) min, t = 3.357, P = 0.001]. The duration of follow-up ranged from 14 to 20 months. There were no postoperative incisional infection, chronic postoperative pain and local foreign body sensation in two groups. In the experimental group, 3 patients suffered scrotal hydrocele as compared 2 patients in the control group. There was no recurrence in the experimental group as compared 2 patients (6.7%) in the control group, which was no significant difference (P > 0.05).
Conclusion:
Lichtenstein repair for pediatric patients aged 6 to 18 years with acellular tissue matrix patch has good results and with limited postoperative complications.

