[Radiofrequency ablation for verapamil-sensitive ventricular tachycardia]
Yong Xie1, Su-Rong Meng, Jian Peng
1Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou 510515,China.
Zhonghua Yi Xue Za Zhi
|February 11, 2012
Summary
Radiofrequency catheter ablation effectively treats verapamil-sensitive ventricular tachycardia (VT) with a low recurrence rate. This procedure offers a safe and curative option for patients with this specific type of VT.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Devices
Background:
- Verapamil-sensitive ventricular tachycardia (VT) is a specific arrhythmia.
- Identifying effective and safe treatment options for VT is crucial.
Purpose of the Study:
- To evaluate the efficacy and safety of radiofrequency catheter ablation for verapamil-sensitive VT.
- To determine the success rate and complication profile of the procedure.
Main Methods:
- 18 patients with verapamil-sensitive VT underwent radiofrequency catheter ablation.
- Ablation targeted Purkinje potentials preceding the QRS complex by at least 20 ms.
- Programmed stimulation was used post-ablation to assess efficacy.
Main Results:
- Successful ablation was achieved in all 18 patients, with VT no longer inducible.
- The optimal ablation target was a Purkinje potential preceding the QRS by 24.0 ± 3.5 ms.
- A low recurrence rate of 11.1% was observed during 3-6 months follow-up, with minor hematoma in 2 patients.
Conclusions:
- Radiofrequency ablation is a safe and effective treatment for verapamil-sensitive VT.
- The procedure demonstrates a low recurrence rate, offering a curative approach.
- Further research may explore long-term outcomes and management of transient resistance.
More Related Videos
12:45Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
28:13Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Related Concept Videos
01:25ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias
Arrhythmia is a condition characterized by an irregular heart rhythm, with ECG changes that differ based on its origin and nature. The types of arrhythmias discussed below include atrial, junctional, and ventricular arrhythmias.Atrial ArrhythmiasPremature Atrial Complexes (PACs): PACs are early atrial beats caused by stress, caffeine, alcohol, electrolyte imbalances, hypoxia, hyperthyroidism, or certain medications (e.g., bronchodilators and decongestants). The ECG shows early P waves with an...
01:20Antiarrhythmic Drugs: Class IV Agents as Calcium Channel Blockers
Class IV antiarrhythmic drugs, such as verapamil and diltiazem, block calcium channels. They primarily affect the heart, slowing the conduction in calcium-dependent tissues like the SA and AV nodes. These drugs manage reentrant supraventricular tachycardia (SVT) and reduce ventricular rate in atrial flutter/fibrillation.
Verapamil, a calcium channel blocker, inhibits calcium movement across myocardial cell membranes and vascular smooth muscle. This results in the dilation of coronary and...
Verapamil, a calcium channel blocker, inhibits calcium movement across myocardial cell membranes and vascular smooth muscle. This results in the dilation of coronary and...
01:25Dysrhythmias VI: Management of Dysrhythmias
Dysrhythmia management involves a multifaceted approach, incorporating pharmacological treatments, medical procedures, surgical interventions, lifestyle modifications, and patient education.Pharmacological ManagementAntiarrhythmic Drugs:Class I (Sodium Channel Blockers): This class includes quinidine and procainamide, which reduce the speed of impulse conduction in the heart, stabilize the cardiac membrane, and control arrhythmias. Quinidine and procainamide are Class IA agents that prolong the...
01:28Dysrhythmias II: Classification of Tachyarrhythmias
Tachyarrhythmias are a type of dysrhythmia where the heart rate exceeds 100 beats per minute. Here are some common types of tachyarrhythmias:Sinus TachycardiaSinus tachycardia originates from increased impulses from the sinus node, leading to an elevated heart rate. It is often triggered by stress, fever, or exercise.Patients may experience palpitations, a sensation of a racing heart, dizziness, and chest discomfort.Causes and Risk Factors: Common causes include physical exertion, emotional...
01:29Disturbances in Heart Rhythm
Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
01:12Antiarrhythmic Drugs: Class III Agents as Potassium Channel Blockers
Class III antiarrhythmic drugs are a group of medications that can prolong action potentials in the heart. They achieve this by blocking potassium channels or enhancing inward currents from sodium channels. However, these drugs have a unique property of "reverse use-dependence," which is most pronounced at slower heart rates and can lead to torsades de pointes—a specific type of arrhythmia. However, it is essential to note that excessive QT interval prolongation—a measure of the heart's...