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Application of an Amplitude-integrated EEG Monitor (Cerebral Function Monitor) to Neonates
Published on: September 6, 2017
Ultrasound evaluation of fetal brain dysfunction based on behavioral patterns
Seiichi Morokuma1, Kotaro Fukushima, Yuka Otera
1Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Higashi-ku, Fukuoka, Japan. morokuma@med.kyushu-u.ac.jp
Brain & Development
|February 11, 2012
Summary
This study introduces a novel ultrasound system to identify fetuses at high risk for poor neurological outcomes. The method shows high sensitivity and specificity for detecting fetal central nervous system impairments.
Area of Science:
- Perinatology
- Fetal Neurology
- Diagnostic Ultrasound
Background:
- Identifying fetuses at risk for adverse neurological outcomes is crucial for timely intervention.
- Current methods may not fully capture subtle fetal brain dysfunction.
Purpose of the Study:
- To evaluate a novel ultrasound system for identifying fetuses at high risk of poor neurological outcomes.
- To assess the correlation between fetal brain function parameters and infant neurological status.
Main Methods:
- A prospective evaluation of 4978 fetuses using a multi-component ultrasound screening system.
- Inclusion criteria: decreased fetal movement, abnormal fetal heart rate, CNS malformations, polyhydramnios.
- Second-stage brief ultrasound evaluation of fetal brain functions in suspicious cases.
Main Results:
- The novel ultrasound system demonstrated 80% sensitivity and 88% specificity in identifying neurological impairment.
- 93 out of 4978 fetuses were identified as suspicious for impairment.
- 26 fetuses underwent detailed fetal brain function assessment.
Conclusions:
- The developed ultrasound evaluation system is a valuable tool for early detection of potential fetal neurological impairment.
- This method can serve as an initial indicator for further fetal central nervous system examination.
- The system is suitable for clinical application in prenatal care settings.
