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Updated: May 25, 2026

Multimodality Diagnosis of Mesenteric Ischemia
05:07

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

Mesenteric artery complications during angioplasty and stent placement for atherosclerotic chronic mesenteric

Gustavo S Oderich1, Tiziano Tallarita, Peter Gloviczki

  • 1Division of Vascular and Endovascular Surgery and Department of Radiology, Mayo Clinic, Rochester, MN, USA. oderich.gustavo@mayo.edu

Journal of Vascular Surgery
|February 11, 2012
PubMed
Abstract

Insights

Mesenteric artery complications (MACs) occurred in 7% of patients undergoing angioplasty and stent placement for chronic mesenteric ischemia (CMI), leading to increased mortality and morbidity. Antiplatelet therapy use was linked to a reduced risk of embolization or thrombosis.

Area of Science:

  • Vascular Surgery
  • Interventional Radiology
  • Gastroenterology

Background:

  • Chronic mesenteric ischemia (CMI) is a debilitating condition often treated with endovascular procedures.
  • Mesenteric artery complications (MACs) can arise during angioplasty and stent placement (MAS), impacting patient outcomes.

Purpose of the Study:

  • To determine the incidence, management strategies, and clinical outcomes of MACs in patients undergoing MAS for CMI.
  • To identify factors associated with MACs and their impact on patient morbidity and mortality.

Main Methods:

  • Retrospective review of 156 patients who underwent 173 MAS procedures for CMI between 1998 and 2010.
  • MACs were defined as procedure-related dissection, stent dislodgement, embolization, thrombosis, or perforation.
  • Outcomes assessed included procedure-related morbidity, mortality, and hospital length of stay.

Main Results:

  • Eleven patients (7%) experienced 14 MACs, including distal embolization, branch perforation, dissection, stent dislodgement, and thrombosis.
  • 45% of patients with MACs required conversion to open repair, and 2.5% experienced early mortality.
  • Patients with MACs had significantly higher mortality (18% vs 1.5%), morbidity (64% vs 19%), and longer hospital stays.

Conclusions:

  • MACs complicate 7% of MAS procedures for CMI, significantly increasing adverse outcomes.
  • Peri-procedural antiplatelet therapy was associated with a lower risk of distal embolization or thrombosis.
  • A trend towards increased MACs was observed with the use of large-profile endovascular systems.

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