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[Prosthetic valve endocarditis].

Y Kioka1, P M Pego-Fernandes, P M Pomerantzeff

  • 1Heart Institute of São Paulo University Medical School.

Kyobu Geka. the Japanese Journal of Thoracic Surgery
|August 1, 1990
PubMed
Summary
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Prosthetic valve endocarditis after valve replacement surgery carries a high mortality risk, especially in emergency cases or when diagnosed within a year of the initial surgery.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Cardiac Surgery

Context:

  • Prosthetic valve endocarditis (PVE) is a serious complication following valve replacement surgery.
  • This study examines PVE cases over a 5-year period from 1983 to 1988.

Purpose:

  • To analyze the clinical characteristics, causative agents, and outcomes of patients undergoing valve replacement for PVE.
  • To identify risk factors associated with increased mortality in PVE patients.

Summary:

  • 28 patients developed PVE among 1,512 valve replacements (1.85%).
  • The mean age was 36.7 years, with 50% having positive blood cultures (Streptococcus viridans most common).
  • Hospital mortality was 28.5%, with higher rates in negative blood cultures, early PVE onset (<1 year), and emergency surgeries.

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Impact:

  • Findings highlight significant mortality associated with PVE, emphasizing the need for prompt diagnosis and management.
  • Identifies critical risk factors (negative cultures, early onset, emergency surgery) that predict poorer outcomes in PVE patients.