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Updated: May 25, 2026

Semiconductor Sequencing for Preimplantation Genetic Testing for Aneuploidy
Published on: August 25, 2019
Confronting ambiguity: identifying options for infants with trisomy 18
Sabrina F Derrington1, April R Dworetz
1Comfort and Palliative Care Team, Children's Hospital Los Angeles, CA, USA. sderrington@chla.usc.edu
Abstract:
Identifying ethically allowable options for infants with trisomy 18 has become more challenging as medical standards of practice shift, based on emerging scientific data and changing societal perceptions of disability. Lack of a stable professional standard of practice ought not prevent ethicists from facilitating a consensus; rather, these "unsettled cases" require an individualized, narrative approach that allows the values of the family and the particularities of each case to provide the necessary additional moral grounding.
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