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[Changes in various biophysical parameters of blood circulation during physical exertion in patients with a mild form
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Mild hypertensive disease impacts cardiac function differently based on left ventricular hypertrophy (LVH). LVH impairs the heart's mechanical performance and adaptive responses in hypertension patients.
Area of Science:
- Cardiology
- Internal Medicine
- Physiology
Abstract:
Sixty four patients (mean age, 46 +/- 3.1 years) with mild hypertensive disease (MHD) were examined. The diastolic pressure recorded in MHD patients in the control period ranged from 95 to 104 mm Hg. There was no evidence of left ventricular hypertrophy (LVH) in 46 patients, whereas 16 had significant signs of LHN. MHD patients without LVH signs showed regularly increased cardiac mechanical performance and its static component through slightly diminished propulsive performance of the myocardium. As moderate LVH evolved in MHD patients, a reduction in kinetic energy of cardiac output was observed, which tended to decrease the static component of mechanical work of the heart, which suggested that the adaptive response of the circulatory system was impaired to some extent.