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Intermolecular hydroacylation: high activity rhodium catalysts containing small-bite-angle diphosphine ligands

Adrian B Chaplin1, Joel F Hooper, Andrew S Weller

  • 1Department of Chemistry, Inorganic Chemistry Laboratories, University of Oxford, South Parks Road, Oxford OX1 3QR, UK.

Journal of the American Chemical Society
|February 14, 2012
PubMed
Summary

Highly efficient rhodium catalysts enable intermolecular hydroacylation of unactivated alkenes and alkynes using aldehydes. These catalysts operate at low loadings, achieving high turnover frequencies for valuable organic synthesis.

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