Related Experiment Video
Updated: May 18, 2026

Single-channel Analysis and Calcium Imaging in the Podocytes of the Freshly Isolated Glomeruli
Published on: June 27, 2015
Physiologic adaptations of the tubuloglomerular feedback system
R C Blantz1, S C Thomson, O W Peterson
1Dept. of Medicine, University of California, School of Medicine, San Diego.
Abstract:
Knowledge of the existence of a tubuloglomerular feedback system has been available for many years. Only recently, however, have tenable hypotheses and supporting experimental data become available which have served to provide details regarding the complex inner workings of this system. The facility for examining this integrated physiologic network has derived, in large part, from the routine ability to perform in vivo micropuncture. We anticipate that further advances in this field will hinge on the development of additional experimental techniques to allow cellular biologic aspects of the system to be closely monitored in situ.
Related Concept Videos
Hormonal Regulation
Positive and Negative Feedback Loops
Introduction to Urinary System
The kidneys are bean-shaped organs located in the retroperitoneal space, on either side of the vertebral column, between the T12 and L3 vertebrae. They are partially protected by the rib cage and surrounded by perirenal fat, which provides cushioning. They are responsible for urine formation and play critical roles in regulating blood pressure, electrolyte levels, and hormone production. The ureters...
Glomerular Filtration Rate and its Regulation
GFR regulation involves two primary intrinsic controls: the myogenic and tubuloglomerular feedback mechanisms.
The myogenic...
Physiology of the Genitourinary System I: Renal Blood Flow and Glomerular Filtration
Physiology of the Genitourinary System II: Tubular Reabsorption and Secretion

