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Updated: May 25, 2026

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models
Published on: August 9, 2012
Relationship between the size of the bladder template and the subsequent bladder capacity in bladder exstrophy
Salvatore Arena1, Alan P Dickson, Raimondo M Cervellione
1Department of Paediatric Urology, Royal Manchester Children's Hospital, Manchester, United Kingdom.
Aim:
The aim of this study is to evaluate the relationship between the size of the bladder template in infants born with bladder exstrophy and the subsequent bladder capacity at the age of 1 and 5 years.
Materials And Methods:
Infants with bladder exstrophy were photographed at birth, and 2 parallel lines were drawn transversally on the photograph across the anterior-superior iliac spines and on the bladder template. The ratio between the 2 lines was calculated, and the bladder templates categorized as (a) small (≥ 4), (b) medium (3-4), and (c) large (<3). Bladder capacity was subsequently measured at 1 and 5 years and considered satisfactory when 60 mL or greater at the age of 1 year and 100 mL or greater at the age of 5 years.
Results:
Sixteen patients were identified. At the age of 1 and 5 years, 81% and 94% had achieved a satisfactory bladder capacity, irrespective of their original template group. Nonetheless, those in group C still showed significantly larger capacities at the age of 5 years than those in groups A and B (P < .05).
Conclusion:
Bladder exstrophy patients, who undergo a successful primary closure, can achieve satisfactory capacities despite smaller bladder templates at birth.
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