Related Experiment Video
Updated: May 25, 2026

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants
Published on: March 29, 2018
Exposure to secondhand smoke may cause dental caries in children
1Department of Pediatric Dentistry, University of Iowa College of Dentistry, Iowa City, IA 52242, USA. rebecca-slayton@uiowa.edu
Purpose/Question:
To determine whether secondhand smoke could be a cause of early childhood caries.
Source Of Funding:
Funding was provided by the Ministry of Health, Labor, and Welfare, Japan, including the following: a Grant-in-Aid for Cancer Research (17-1); the Health and Labor Sciences Research Grants for Clinical Cancer Research (H19-010); and Comprehensive Research on Cardiovascular and Life-Style Related Diseases (H19-007). Additional funding was provided by a research grant from the 8020 Promotion Foundation.
Type Of Study/Design:
Systematic review.
Level Of Evidence:
Level 2: Limited-quality, patient-oriented evidence.
Strength Of Recommendation Grade:
Grade B: Inconsistent, limited-quality patient-oriented evidence.
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