Corpus callosotomy for treatment of pediatric refractory status epilepticus
Hansel M Greiner1, Jan-Mendelt Tillema, Barbara E Hallinan
1Department of Pediatrics, Division of Child Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA. hansel.greiner@cchmc.org
Insights
Medically refractory status epilepticus (RSE) is a severe condition in children with no clear treatment guidelines. Complete corpus callosotomy (CC) surgery offers a potential solution for prolonged RSE cases lacking focal epilepsy origins.
Area of Science:
- Pediatric Neurology
- Neurosurgery
- Epileptology
Background:
- Medically refractory status epilepticus (RSE) presents significant morbidity and mortality risks in pediatric populations.
- Current treatment protocols for RSE lack evidence-based guidelines, necessitating exploration of alternative therapeutic strategies.
Abstract:
Medically refractory status epilepticus (RSE) causes high morbidity and mortality in children. There are no evidence-based guidelines for treatment. Epilepsy surgery is a treatment option for RSE. We describe a 9-year-old boy treated successfully for RSE with complete corpus callosotomy (CC). Epilepsy surgery should be considered for prolonged RSE. In the absence of evidence of focal epileptogenesis, complete corpus callosotomy may be effective in select cases.
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