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Updated: May 25, 2026

Conjunctival Commensal Isolation and Identification in Mice

Conjunctival Commensal Isolation and Identification in Mice

Published on: May 1, 2021

Mycobacterium massiliense keratitis.

Xiaowei Liu¹, Ying Zhao, Yuanquan Yang

¹Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.

Optometry and Vision Science : Official Publication of the American Academy of Optometry

|February 14, 2012

Summary

This summary is machine-generated.

A case of keratitis caused by Mycobacterium massiliense, a non-tuberculous mycobacteria, was successfully treated. Early diagnosis and targeted antibiotic therapy with amikacin and levofloxacin are crucial for favorable outcomes in corneal infections.

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Area of Science:

Ophthalmology
Microbiology
Infectious Diseases

Background:

Non-tuberculous mycobacteria (NTM) can cause ocular infections.
Mycobacterium massiliense is an NTM subtype that can lead to severe keratitis.

Observation:

A 23-year-old man developed keratitis after corneal trauma and a foreign body removal.
Initial conventional therapy failed, with persistent redness, lesion, and vision loss.

Findings:

Corneal scraping revealed acid-fast bacilli, identified as Mycobacterium massiliense via PCR and sequencing.
Successful treatment was achieved with amikacin and levofloxacin based on susceptibility testing.

Implications:

Multiple gene sequencing is vital for accurate M. massiliense identification.
Prompt diagnosis and treatment of M. massiliense keratitis can prevent vision-impairing sequelae like corneal scarring and neovascularization.