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Updated: May 25, 2026

One-step Negative Chromatographic Purification of Helicobacter pylori Neutrophil-activating Protein Overexpressed in Escherichia coli in Batch Mode
Published on: June 18, 2016
The Multiple Carbohydrate Binding Specificities of Helicobacter pylori
1Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, Göteborg University, P.O. Box 440, 405 30 Göteborg, Sweden, Susann.Teneberg@medkem.gu.se.
Abstract:
Persistent colonization of the human stomach by Helicobacter pylori is a risk factor for the development of peptic ulcer disease and gastric cancer. Adhesion of microbes to the target tissue is an important determinant for successful initiation, establishment and maintenance of infection, and a variety of different candidate carbohydrate receptors for H. pylori have been identified. Here the different the binding specifities, and their potential role in adhesion to human gastric epithelium are described. Finally, recent findings on the roles of sialic acid binding SabA adhesin in interactions with human neutrophils and erythrocytes are discussed.
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