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Updated: May 25, 2026
Direct Observation of Phagocytosis and NET-formation by Neutrophils in Infected Lungs using 2-photon Microscopy
Published on: June 2, 2011
A nebulized intra-tracheal rat model of invasive pulmonary aspergillosis
Guillaume Desoubeaux1, Jacques Chandenier
1Parasitologie-Mycologie-Médecine tropicale, Centre Hospitalier Régional et Universitaire, Tours, France.
Abstract:
Animal models are particularly useful for the study of many infectious diseases, including those caused by fungi. Invasive pulmonary aspergillosis is most frequently studied in mouse models. We present here an animal model of this disease based on undernourished immunocompromised rats infected with Aspergillus fumigatus spores by intra-tracheal nebulisation.
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